The Clinical Chemistry learning guide focuses on clinical chemistry, which encompasses a wide variety of tests and is a major area of concentration in hospital and reference core laboratories. Clinical chemistry uses many different methodologies, manual and fully automated tests, examines both very common and esoteric analytes, mixes basic chemistry with biochemistry, engineering, informatics andother disciplines, and overlaps with other areas of concentration, in particular, toxicology and endocrinology.
The Proteins learning guide is an overview of the pathophysiological principles and the major disease states related to important serum proteins. It provides an understanding of clinically important serum proteins and their use in diagnosing and managing common clinical situations. It reviews the different important analytical techniques used to identify and quantify these proteins. It also describes approaches to standardizing or harmonizing protein assays. The guide is intended to be used as a reference for the application of clinical laboratory tests and interpretation of laboratory results.
The Therapeutic Drug Monitoring learning guide provides an overview of drug concentration measurements in body fluids as an aid to management of drug therapy for the cure, alleviation or prevention of disease. It has long been customary to adjust the dosage of drugs according to the characteristics of the individual being treated and the response obtained. Therapeutic Drug Monitoring now has an established place in enabling optimization of therapy with certain agents.Download
Chronic Kidney Disease (CKD), one form of kidney dysfunction, is increasingly recognized as a major public health concern. The continuum of CKD ranges from mild kidney damage to end-stage renal disease (ESRD). Early detection and appropriate management can help delay progression to kidney failure and the development of complications.
Diagnosis of CKD is based on laboratory criteria and has important implications for patients, with emotional, pharmacological, and socioeconomic impact. New practice guidelines and the standardization of renal function tests offer an opportunity to greatly improve the health of CKD patients and reduce the cost of care.
The Shedding Light on Renal Disease monograph describes the incidence and physiology of CKD and associated complications, diagnostic guidelines and tests, and laboratory assessment of renal function.
Chronic Kidney Disease (CKD) Learning Guide
Provides an overview of chronic kidney disease and explains the complications, diagnosis and management of the disease.
The Six Sigma Based Quality Control learning guide provides the basics of statistical quality control (SQC) in a laboratory. SQC is an essential laboratory practice to ensure reported test results achieve the quality required for intended medical use. Analytical quality demands continue to increase as physicians and patients depend on test results for optimal diagnosis and treatment. Although modern highly automated systems provide many function checks to ensure proper operations to produce accurate results, no analytical system is perfectly stable. Laboratories need SQC to provide a final independent check to detect performance changes potentially causing medical errors.Download
The Diabetes learning guide offers an overview of diabetes and the use of glycated hemoglobin (HbA1c) as a clinical tool for general health screening and monitoring for patients suspected of having diabetes. This learning guide reviews reference methodologies, available assay methods, standardization and certification. It also reviews the physiology of HbA1c and its hemoglobin variants or derivatives, and the recommendations/precautions for using HbA1c in clinical practice.Download
The Thyroid Learning Guide serves the basic educational needs of health care professionals associated with thyroid function testing. Thyroid disease is the most prevalent endocrine disorder known. The onset of thyroid disease is often misunderstood by the patient. This is because the clinical manifestations of thyroid dysfunction vary considerably among patients in their characteristics and severity. Successful diagnosis and management of thyroid disease requires close collaboration between the physician, clinical laboratory and the patient. This guide provides an overview of thyroid gland function and the diseases and treatments associated with thyroid gland dysfunction.Download
The Cardiac learning guide is an overview of the anatomy and physiology of a healthy heart. It also provides an explanation of the pathophysiology of two common conditions – acute coronary syndrome and heart failure. It reviews information on the role of cardiac biomarkers in the diagnosis, prognosis, risk stratification, and therapy monitoring of various heart conditions. The Guide is intended to serve the basic educational needs of healthcare professionals who are involved in the laboratory or who manage patients who have or are at risk of developing heart disease.Download
Several learning guides covering the fundamentals of hematology and coagulation have been developed to help seasoned clinical laboratory personnel refresh their knowledge, or provide introductory concepts for those that are new to clinical laboratory medicine. To learn more about our hematology solutions visit Hematology Analyzers and Systems.
Hematology Learning Guide
An overview of blood physiology, red and white blood cells, platelets and abnormalities associated with these cellular components. It also provides additional information regarding the clinical implications of the complete blood count (CBC) that may also require additional follow-up testing.
RBC Indices & Extended RBC Parameters Learning Guide
Provides an overview of erythropoiesis, review traditional and advanced RBC indices & parameters and their clinical utility, and preanalytical variables and interfering substances affecting RBC count and indices.
Platelet Counting Learning Guide
Provides an overview of platelet origin and function. The guide disscusses the analytical characteristics of platelet counting methods that are determinant factors for their clinical use.
Analysis of Body Fluids Learning Guide
Provides an overview of body fluid types, their composition, methods of analysis and clinical significance in disease diagnosis.
Quality Control in the Hematology Laboratory Learning Guide
Provides basic quality control concepts in the hematology laboratory and how to use basic quality control procedures to ensure the best results from your analyzer.
Middleware Use & Operation Learning Guide
Serves as a primer and provides a basic overview of middleware, its use, capabilities and benefits in general laboratory operations, with a focus on applications in Hematology.
Coagulation Learning Guide
Covers the components that make up coagulation and the different hemostasis stages and how they form. Standard clinical screenings and testing procedures are also provided and how patterns found may lead to solid findings as well as follow up testing.
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