Why Are Physicians and Laboratories worried about Biotin?

Millions of people are taking biotin for the overall health benefits in hair, skin and nails. However, physicians and labs are concerned because biotin may interferes with immunoassay lab tests that utilize the biotin-streptavidin method and can lead to misdiagnosis or mistreatment.

There are other test methods available, including those provided by Abbott ARCHITECT, that do not involve biotin-streptavidin capture method and therefore are not impacted. 

For more information and the steps to take to eliminate your risk, please help identify your role in the Biotin-care pathway:

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Consumers

Find answers to your questions about biotin and its impact on your laboratory tests.

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Physicians

Find out how to remove the risk of misdiagnosis due to inaccurate results from biotin interference.

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Laboratorians

Find out how to provide accurate test results not impacted by biotin.

  1. Nielsen FDM Data Ending 03/26/16.
  2. https://www.amazon.com/s/ref=nb_sb_noss_1?url=search-alias%3Daps&field-keywords=biotin.
  3. Google analytics: September 2016.
  4. Zempleni J, Kuroishi T. Biotin. Adv Nutr. 2012;3:213-214. 
  5. Combs GF. Biotin. In: Combs, GF. The Vitamins: Fundamental Aspects in Nutrition and Health. San Diego, CA: Elsevier, Inc.; 2008: 331-3.
  6. Kummer, S. NEJM August 2016: Biotin Treatment Mimicking Graves’ Disease.
  7. Saint Paul LP, Debruyne D, Bernard D, Mock DM and Defer GL. Pharmacokinetics and pharmacodynamics of MD1003 (high-dose biotin) in the treatment of progressive multiple sclerosis, 2016; Expert Opinion on Drug.
  8. Fernandez-Mejia,  C. Journal of Nutritional Biochemistry 16 (2205) 424-427.
  9. Seaborg, E. January 2016: Thyroid Month: Beware of Biotin, Endocrine News, 2016. 
  10. Paxton A.  Beauty fad’s ugly downside: test interference.  CAP Today, September 20, 2016.
 

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