Core Laboratory 
Core Laboratory 

Sepsis

Sepsis is the body’s overwhelming and life-threatening response to infection that can lead to tissue damage, organ failure and death.1 In the United States, one person is diagnosed with sepsis every 20 seconds.1 In total, 1.6 million people are diagnosed with sepsis each year.1

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Transform Your Laboratory

 

Sepsis is the leading cause of death in U.S. Hospitals with an in-hospital mortality rate of 16%1

 

Chance of Mortality from sepsis increases 8% for every hour that treatment is delayed1

 

Sepsis is the most expensive in-patient cost in U.S. hospitals (over $24 billion each year)1


Procalcitonin and Sepsis

Procalcitonin (PCT) helps determine if a patient has a bacterial infection (sepsis), the severity of the infection and whether the patient is responding to therapy.2 PCT is a more accurate diagnostic parameter for sepsis, a better predictor of mortality and a more reliable marker than other biomarkers, including C-reactive protein (CRP), Interleukins and Lactate levels.3

Sepsis PCT Molecule Image

ARCHITECT B.R.A.H.M.S. PCT4

  • Provides clinicians a risk assessment of critically ill patients on their first day of intensive care unit (ICU) admission for progression to severe sepsis and septic shock.
  • Aid in decision making on antibiotic discontinuation for patients with suspected or confirmed sepsis.
  • Excellent clinical sensitivity with a Limit of Quantitation (LoQ) of 0.01 ng/mL allowing for early indication, antibiotic stewardship and negative predictive values.
1. Sepsis Alliance Website, http://www.sepsis.org/resources/infographics, accessed September 2017.
2. Thermo Scientific B-R-A-H-M-S PCT Improving Infection Management.
3. Shiferaw, et al. The Role of Procalcitonin as a Biomarker in Sepsis. J Infect Dis Epidemiology. 2016; 2:006 Vol 2.
4. ARCHITECT B•R•A•H•M•S Package Inserts, G1-0601 R01, June 2017.
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Resources

Raising Awareness About Sepsis

Abbott is committed to increasing awareness about sepsis and has developed several educational resources to help clinicians and laboratorians learn more about sepsis.

Video: Emergency Department Perspective

Video: Intensive Care Unit Perspective

Video: Pharmacy Perspective

WEBINAR: CLINICAL APPLICATIONS IN USING PROCALCITONIN
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