High sensitive troponin-I

TRoponin Image
TRoponin Image
TRoponin Image

Rapidly diagnosing and triaging chest pain patients

Emergency departments worldwide continually face the challenge of rapidly diagnosing and triaging chest pain patients.

Patient test results can help clarify the clinical picture. Timely action on cardiac laboratory results is critical and may improve patient outcomes.

The laboratory can help address some challenges by offering cardiac tests that are accurate, reliable and fast.

The enhanced sensitivity and precision of high sensitivity troponin assays combined with sex-specific cut-offs allows faster and more accurate assessment of suspected myocardial infarction1, particularly in women, who tend to have lower circulating levels of troponin even when having an MI. 2

The value of troponin

Alinity and ARCHITECT High Sensitive Troponin-I results may enable an easier management of patients with suspect Acute Myocardial Infarction (AMI) through:

Excellent precision and high sensitivity

This assay complies with the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) requisites for high sensitive troponin analytical characteristics, including low end detection in a normal healthy population and imprecision of less than 6% CV at the medical decision points.

Sex-specific cutoffs

Establish accurate cutoff values in males and females with excellent precision. Sex-specific cutoffs have been validated in various study cohorts.

Improved emergency department throughput

A "true" high sensitive assay for cardiac troponin I, that allows a reduction in the testing interval of patients admitted for suspect AMI from 6 hours to 3 hours or even down to 1 hour, as advocated by the most recent European Society of Cardiology (ESC) guidelines.


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  1. Alinity i STAT High Sensitive Troponin-I Package Insert H05938R03
  2. Shah ASV, BMJ. 2015;350:g7873:1-8.